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Last Loaded on Web: Monday, April 01, 2013
BIOSIS® Toxicology contains citations from Biological Abstracts® (BA), and Biological Abstracts/Reports, Reviews, and Meetings® (BA/RRM) (formerly BioResearch Index®), the major publications of BIOSIS®, that focus on toxicology and related topics. Records are drawn from journal articles, conference papers, monographs and book chapters, notes, letters, and reports, as well as original research. U.S. patent records are also included.
Abstracts are available for records beginning in 1976.
USE FILE 157to search for highly focussed literature on all aspects of toxicology. USE MAJOR CONCEPTS FOR EMPHASISS CELL BIOLOGY?/MCUSE THE (L) OPERATORto link terms with their modifiers or roles: S BACTERIA(L)MICROORGANISMS/DEUSE LIMITSfor human subjects, conference papers: S S1/HUMAN; S S5/CONFUSE MAPto search CAS® Registry Numbers in another file: MAP RN TEMP |
All aspects of toxicology are covered, as they relate to:
| Dates Covered: | 1969 to present |
|---|---|
| File Size: | 1,610,222 records as of December 2005 |
| Update Frequency: | Weekly |
None
| ACRONYM | CATEGORY NAME |
|---|---|
| TOXSEARC | Toxfile, IPA, Biosis toxicology |
|
BIOSIS Toxicology is provided by BIOSIS, a Thomson business. Questions concerning file content should be directed to: Customer Support Desk 3501 Market Street Philadelphia, PA 19104
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| DIALOG(R)File 157:Biosis Toxicology | |
| (c) 2003 BIOSIS. All rts. reserv. | |
| AA= | 0000009882 BIOSIS NO.: 200200270290 |
| /TI | Toxicity of tetracyclines and tetracycline degradation products to |
| environmentally relevant bacteria, including selected | |
| tetracycline-resistant bacteria | |
| AU= | AUTHOR: Halling-Sorensen B (Reprint); Sengelov G; Tjornelund J |
| CS= | AUTHOR ADDRESS: Section of Environmental Chemistry, Dept. of Analytical and |
| Pharmaceutical Chemistry, Royal Danish School of Pharmacy, | |
| Universitetsparken 2, DK-2100, Copenhagen O, Denmark**Denmark | |
| JN=,SO= | JOURNAL: Archives of Environmental Contamination and Toxicology 42 (3): |
| PY= | p263-271 April, 2002 |
| MEDIUM: print | |
| SN= | ISSN: 0090-4341 |
| DT= | DOCUMENT TYPE: Article |
| RT= | RECORD TYPE: Abstract |
| LA= | LANGUAGE: English |
| /AB | ABSTRACT: Tetracyclines used in veterinary therapy invariably will find |
| their way as parent compound and degradation products to the agricultural | |
| field. Major degradation products formed due to the limited stability of | |
| parent tetracyclines (tetracycline, chlortetracycline, and | |
| oxytetracycline) in aqueous solution were theoretically identified at | |
| various environmental conditions, such as pH, presence of chelating | |
| metals, and light. Their potency was assessed on sludge bacteria, | |
| tetracycline-sensitive soil bacteria, and tetracycline-resistant strains. | |
| Several of the degradation products had potency at the same concentration | |
| level as tetracycline, chlortetracycline, and oxytetracycline on both the | |
| sludge and the tetracycline-sensitive soil bacteria. Further, both | |
| 5a,6-anhydrotetracycline and 5a,6-anhydrochlortetracycline had potency on | |
| tetracycline-resistant bacteria supporting a mode of action different | |
| from that of the parent compounds. | |
| RN=,/NA,NA= | REGISTRY NUMBERS: 57-62-5: chlortetracycline; 79-57-2: oxytetracycline; |
| 60-54-8: tetracycline; 60-54-8: tetracyclines | |
| DESCRIPTORS: | |
| /DE,/MC | MAJOR CONCEPTS: Pharmacology; Pollution Assessment Control and Management; |
| Toxicology | |
| BN=,/DE,/OI,OI= | BIOSYSTEMATIC NAMES: Bacteria--Microorganisms |
| /DE,/OI,OI= | ORGANISMS: bacteria (Bacteria)--environmentally relevant, |
| tetracycline-resistant, tetracycline-sensitive; sludge bacteria | |
| (Bacteria) | |
| BC=,/DE,/OI,OI= | COMMON TAXONOMIC TERMS: Bacteria; Eubacteria; Microorganisms |
| /DE,/NA,NA=,/SY,SY= | CHEMICALS & BIOCHEMICALS: 5-alpha,6-anhydrochlortetracycline--pollutant, |
| toxicity; 5-alpha,6-anhydrotetracycline--pollutant, toxicity; | |
| chelating metals; chlortetracycline--antibacterial-drug, | |
| antiinfective-drug, pollutant, toxicity; oxytetracycline-- | |
| antibacterial-drug, antiinfective-drug, pollutant; tetracycline-- | |
| antibacterial-drug, antiinfective-drug, pollutant; tetracycline | |
| degradation products--pollutant, toxicity; tetracyclines-- | |
| antibacterial-drug, antiinfective-drug, pollutant, toxicity | |
| /DE,/MQ | METHODS & EQUIPMENT: veterinary therapy--therapeutic method |
| /DE,/MI | MISCELLANEOUS TERMS: light; pH |
| CONCEPT CODES: | |
| CC=,CN= | 10060 Biochemistry studies - General |
| 12512 Pathology - Therapy | |
| 22002 Pharmacology - General | |
| 22501 Toxicology - General and methods | |
| 22504 Toxicology - Pharmacology | |
| 22506 Toxicology - Environment and industry | |
| 31000 Physiology and biochemistry of bacteria | |
| 37015 Public health - Air, water and soil pollution | |
| 38502 Chemotherapy - General, methods and metabolism | |
| 38504 Chemotherapy - Antibacterial agents | |
| BIOSYSTEMATIC CODES: | |
| BC=,BN= | 05000 Bacteria |
| DIALOG(R)File 157:Biosis Toxicology | |
| (c) 2004 BIOSIS. All rts. reserv. | |
| AA= | 0000006966 BIOSIS NO.: 200200240531 |
| /TI | Method for antagonizing inhibition effects of alcohol on cell adhesion |
| AU= | AUTHOR: Charness Michael E (Reprint); Wilkemeyer Michael F |
| CS= | AUTHOR ADDRESS: Waban, MA, USA**USA |
| JN=,SO= | JOURNAL: Official Gazette of the United States Patent and Trademark Office |
| PY= | Patents 1256 (3): Mar. 19, 2002 |
| MEDIUM: e-file | |
| PN=,PD= | PATENT NUMBER: US 6359015 PATENT DATE GRANTED: March 19, 2002 20020319 |
| CL=,PA=,CO= | PATENT CLASSIFICATION: 514-724 PATENT ASSIGNEE: The United States of |
| America as represented by the Department of Veterans Affairs, Washington, | |
| DC, USA PATENT COUNTRY: USA | |
| SN= | ISSN: 0098-1133 |
| DT= | DOCUMENT TYPE: Patent |
| RT= | RECORD TYPE: Abstract |
| LA= | LANGUAGE: English |
| /AB | ABSTRACT: A method of antagonizing inhibition effects of alcohol on cell |
| adhesion, includes contacting a cell-adhesion molecule expressing cell | |
| with an effective amount of a compound, wherein the compound comprises an | |
| alcohol with five or more carbons. More particularly, the compound | |
| comprises 1-pentanol, 1-octanol, and structural derivatives thereof. | |
| RN=,/NA,NA= | REGISTRY NUMBERS: 111-87-5: 1-octanol; 71-41-0: 1-pentanol |
| DESCRIPTORS: | |
| /DE,/MC | MAJOR CONCEPTS: Cell Biology; Methods and Techniques; Nervous System-- |
| Neural Coordination; Pharmacology; Toxicology | |
| /DE,/PS,PS= | ORGANISMS: PARTS ETC: neuron--nervous system |
| /DE,/DS | DISEASES: alcoholism--behavioral and mental disorders, toxicity, drug |
| therapy | |
| /DE,/MH | MESH TERMS: Alcoholism (MeSH) |
| /DE,/NA,NA=,/SY,SY= | CHEMICALS & BIOCHEMICALS: 1-octanol; 1-pentanol |
| /DE,/MQ | METHODS & EQUIPMENT: method for antagonizing inhibition effects of |
| alcohol on cell adhesion--pharmacological method | |
| /DE,/MI | MISCELLANEOUS TERMS: cell adhesion |
| CONCEPT CODES: | |
| CC=,CN= | 02502 Cytology - General |
| 02506 Cytology - Animal | |
| 07004 Behavioral biology - Human behavior | |
| 12512 Pathology - Therapy | |
| 20504 Nervous system - Physiology and biochemistry | |
| 21004 Psychiatry - Addiction: alcohol, drugs, smoking | |
| 22002 Pharmacology - General | |
| 22501 Toxicology - General and methods | |
| SEARCH SUFFIX |
DISPLAY CODE |
FIELD NAME |
INDEXING |
SELECT EXAMPLES |
|---|---|---|---|---|
| None | None | All Basic Index Fields | Word | S NEUROTOXICITY(W)GLUTAMATE? |
| /AB | AB | Abstract1 | Word | S VETERINARY(W)THERAP?/AB |
| /CO | CO | Company Name (Patent Assignee)2,3,5 | Word | S ALLERGAN(W)SALES/CO |
| /DE | DE | Descriptor5,6 | Word & Phrase |
S BACTERIA/DE S SLUDGE BACTERIA?/DE |
| /DS | DS | Diseases and Disease Modifiers4,5 | Word & Phrase |
S ALCOHOLISM/DS S ALCOHOL WITHDRAWAL?/DS |
| /GE | GE | Gene Name2,5,7 | Word & Phrase |
S STAPHYLOCOCCUS(W)AUREUS/GE S STAPHYLOCOCCUS AUREUS?/GE |
| /GN | GN | Geographic Name2,5,8 | Word & Phrase |
S (US OR USA OR UNITED(W)STATES)/GN S BAJA CALIFORNIA?/GN |
| /MC | MC | Major Concepts5,8,9 | Word & Phrase |
S TOXICOLOGY/MC S POLLUTION ASSESSMENT/MC |
| /MH | MH | MeSH Heading5,10 | Word & Phrase |
S ALCOHOLISM/MH S ALCOHOLISM (MESH)/MH |
| /MI | MI | Miscellaneous Descriptors5 | Word & Phrase |
S LIGHT/MI S CELL ADHESION/MI |
| /MQ | MQ | Methods and Equipment4,5 | Word & Phrase |
S CELL(W)ADHESION/MQ S VETERINARY THERAP?/MQ |
| /NA | NA | Chemical Name2,5,8 | Word & Phrase |
S ANTIINFECTIVE(W)DRUG/NA S CHELATING METAL?/NA |
| /OI | OI | Organism Names and Modifiers2,5,11 | Word & Phrase |
S BACTERIA/OI S BACILLUS ANTHRACIS?/OI |
| /PS | PS | Organism Parts, Structures and Systems4,5 | Word & Phrase |
S CIRCULATORY(W)SYSTEM/PS S NEURON(S)NERVOUS SYSTEM?/PS |
| /SQ | SQ | Molecular Sequence Databank Number4,5 | Word & Phrase |
S AMINO(W)ACID?/SQ S AJ315962/SQ/SQ |
| /SY | SY | Chemical Name2,5,8 | Word & Phrase |
S TETRACYCLINE/SY S CHELATING METALS/SY |
| /TI | TI | Series Title | Word | S INTERNATIONAL(W)CONGRESS?/TI |
| /TI | TI | Title | Word | S TETRACYCLINE(W)RESISTAN?/TI |
| /TM | TM | Time (Geologic) | Word & Phrase |
S CENOZOIC/TM S MESOZOIC?/TM |
1 Abstracts for BA records from July 1976 forward and for BA/RRM book synopses from 1985 forward.
2 Searchable in the Basic Index and in the Additional Indexes.
5 Also searchable as /DE, /DF, /KW and displayable with DE.
6 Includes Common Taxonomic Terms, Biosystematic Names, Chemical Names, Diseases, Geographic Name,Major Concepts, Methods & Equipment, Miscellaneous Descriptors, Organism Names, Sequence Data, Synonyms, Time Descriptors, and MeSH Terms.
9 Truncation is recommended for phrase-indexed /MC terms.
11 Includes Biosystematic Names, Organisms, Biosystematic Classification Names and Super Taxa.
| SEARCH PREFIX |
DISPLAY CODE |
FIELD NAME |
INDEXING |
SELECT EXAMPLES |
|---|---|---|---|---|
| AA= | AA | BIOSIS Accession Number | Phrase | S AA=200200270290 |
| AU= | AU | Author | Phrase | S AU=HALLING-SORENSEN B |
| None | AZ | DIALOG Accession Number | ||
| BC= | BC | Biosystematic Classification or Super Taxa Name | Phrase | S BC=BACTERIA S BC=75403 |
| BN= | BN | International Standard Book Number (ISBN) | Phrase | S BN=0-387-98805-X |
| BN= | DE | Biosystematic Name8,11 | Phrase | S BN=BACTERIA? |
| CC= | CC | Concept Code | Phrase | S CC=22501 |
| CL= | CL | Patent Classification | Phrase | S CL=514-724 |
| CL= | LO | Conference Location8,13 | Word | S CL=(FORT(W)WORTH(W)TX) |
| CN= | CN | Concept Name | Phrase | S CN=PUBLIC HEALTH? |
| None | CN | Patent Country | ||
| CO= | CO | Company Name(Patent Assignee)2,3,5 | Phrase | S CO=THE UNITED STATES? |
| CS= | CS | Corporate Source14 | Word & Phrase |
S CS=(DANISH(W)SCHOOL?) S CS=APPLIED ALGAE RESEARCH? |
| CT= | CT | Conference Title13 | Word | S CT=(DIGESTIVE(W)DISEASE) |
| CY= | CY | Conference Year8,13 | Phrase | S CY=2002 |
| DA= | DA | Conference Date8,13 | Word | S DA=20020519 |
| DT= | DT | Document Type13 | Phrase | S DT=ARTICLE |
| EC= | EC | Enzyme Commission Number8 | Phrase | S EC=EC 2.5.1.18 |
| GE= | GE | Gene Name2,5,7 | Phrase | S GE=G-FOS GENE |
| GN= | GN | Geographic Name2,5,8 | Word & Phrase |
S GN=(UJI(W)JAPAN) S GN=UKRAINE (EUROPE)? |
| JN= | JN | Journal Name | Phrase | S JN=ARCHIVES OF ENVIRONMENTAL CONTAM? |
| LA= | LA | Language14 | Phrase | S LA=ENGLISH |
| None | ME | Medium Type | ||
| NA= | NA | Chemical Name2,5,8 | Phrase | S NA=5-ALPHA,6-ANHYDROCHLOR? |
| NT= | NT | New Taxa8 | Phrase | S NT=NEW TAXA |
| OI= | OI | Organism Names2,5,8,15 | Phrase | S OI=ARTHROPODS |
| PA= | PA | Patent Assignee3 | Word & Phrase |
S PA=(UNITED(W)STATES) S PA=RHONE-POULENC? |
| PD= | PD | Patent Date3 | Phrase | S PD=20020319 |
| PN= | PN | Patent Number3 | Phrase | S PN=US 6359015 |
| None | PR | BIOSIS Print Number | ||
| PU= | PU | Publisher8 | Word & Phrase |
S PU=(HUMANA(W)PRESS) S PU=HUMANA PRESS? |
| PY= | PY | Publication Year | Phrase | S PY=2002 |
| RN= | RN | CAS(R) Registry Number | Phrase | S RN=57-62-5 |
| RT= | RT | Record Type | Phrase | S RT=ABSTRACT |
| SN= | SN | International Standard Serial Number (ISSN) | Phrase | S SN=0090-4341 S SN=00904341 |
| SO= | SO | Source Information17 | Word | S SO=(OFFICIAL(W)GAZETTE AND 1256) |
| SP= | SP | Sponsor4 | Word & Phrase |
S SP=(AMERICAN(W)SOCIETY(1W)MICROBIOLOGY) S SP=AMERICAN SOCIETY? |
| SY= | SY | Chemical Name2,5,8 | Phrase | S SY=OXYTETRACYCLINE? |
| UD= | None | Update | Phrase | S UD=9999 |
12 Available for records from 1989 forward.
13 For meetings and conferences use /CONF limit.
14 In BA records since January 1978: in BA/RRM records since January 1980.
15 Does not include modifiers.
17 Search and Display include Journal Name, Volume, Issue, Pagination, and Publication Year.
| SUFFIX | FIELD NAME | EXAMPLES |
|---|---|---|
| /ABS | Abstract Present | S BACTERIA/ABS |
| /CONF | Also /MEETING; Conference Papers and Meetings | S GENOME/CONF |
| /ENG | English Language | S S3/ENG |
| /HUMAN | Human Subject | S S4/HUMAN |
| /YYYY | Publication Year | S S2/2001:2002 |
| SORTABLE FIELDS | EXAMPLES |
|---|---|
| AU, CS, JN, PY, TI | SORT S3/ALL/AU PRINT S5/5/1-86/AU/TI |
| RANK FIELDS | EXAMPLES |
|---|---|
| All phrase- and numeric-indexed fields in the Additional Indexes can be ranked. | RANK AU S3 |
| MAP FIELDS | EXAMPLES |
|---|---|
| PA, PN, PU, RN, SY, SYRN | MAP RN TEMP S2 |
| User-defined formats may be specified using the display codes indicated in the Search Options tables. | TYPE S2/AU,TI,SO/1-5 |
| NO. |
DIALOGWEB FORMAT |
RECORD CONTENT |
|---|---|---|
| 1 | -- | DIALOG Accession Number |
| 2 | -- | Full Record except Abstract |
| 3 | Medium | Bibliographic Citation18 |
| 4 | -- | Full Record with Tagged Fields1 |
| 5 | -- | Full Record1 |
| 6 | Free | Title and Publication Year |
| 7 | Long | Bibliographic Citation and Abstract1 |
| 8 | Short | Title, Indexing and Publication Year |
| 9 | Full | Full Record1 |
| K | -- | KWIC (Key Word In Context) displays a window of text; may be used alone or with other formats |
18 Includes the patent number.
| FIELD NAME | EXAMPLES | ||
|---|---|---|---|
| DIALOG Accession Number | TYPE 00056397/3 DISPLAY 00023589/AU,TI PRINT 00038167/9 |
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501-1000 8.00
1001 or more 10.00
